Contemporary Evolution in CRISPR–CAS9 System Technology and their Uses in Treatment of Human Common Diseases: A Review
نویسندگان
چکیده
Gene therapy has proven its potential in treatment of several human diseases. Most recent method a longline the genome-editing-techniques is called “A Clustered-Regularly-Interspaced-Short-PalindromicRepeat-associated-protein9” abbreviated as CRISPR-Cas9. The scientists and researcher have long soughtto control, modification DNA that consider “the code life”. CRISPR-Cas9technology isoffer very important improvements differ about other gene-editing.technologies, it’s uncomplicated toapply & low-cost, also comparatively high degree efficiency precision . This technologyuses “.ribonucleic acid.(RNA)-guided. Deoxyribonucleic. acid-DNA-endonuclease.”, Cas9, whichinduces double-strand breaks (DSBs) target site, DSBs was repaired by use variety ofcellular DNA-repair systems leading to changes sites, technology be effectiveto investigation, prevention, diseases.This review summarizes contemporary evolution CRISPR –Cas9 system their uses intreatment common
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ژورنال
عنوان ژورنال: Medico-Legal Update
سال: 2021
ISSN: ['0971-720X', '0974-1283']
DOI: https://doi.org/10.37506/mlu.v21i2.2878